Ramiel is one of the two final bosses in Painkiller: Resurrection, alongside Astaroth.
Ramiel is a fallen angel that has sided with Astaroth to take over Purgatory. He resembles Sammael, although he doesn't make use of his dark wings. Instead, he tries to reach the player and hurt him with his hands, so it is advised to stay away from him. Keep in mind he can also occasionaly attack from distance. He is immune to our fire as long as his demon companion is alive.
The Ramiel&Astaroth duo is the only time in the franchise we encounter two bosses at once. They both appear at the end of High Seas in Painkiller: Resurrection.